Advanced breast cancer is very easily recognizable by knowing operbilitas Heagensen following criteria:
* there is extensive edema in breast skin (over 1 / 3 area of breast skin);
* the existence of satellite nodules on the skin of the breast;
* breast cancer types of mastitis karsinimatosa;
* There parasternal model;
* There supraklavikula nodules;
* of the edema arm;
* the existence of distant metastases;
* and there are two of the signs of locally advanced, namely skin ulceration, skin edema, skin fixed to the thoracic wall, axillary lymph node 2.5 cm in diameter, and axillary lymph nodes attached to each other.